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We provide most comprehensive Customer Service
Experienced technical support team Confidentiality guaranteed Column selection guidance Troubleshooting advice. Free application searches World’s largest HPLC applications data base Free method strategy consultancy Method development and optimisation service Column validation service Samples chromatographed on a wide range of columns Wide range of chromatography materials, equipment and plants Extensive range of column dimensions Customer supplied packing Batch reservation service Unrivalled experience in the manufacture of superior quality columns from microbore to preparative scale dimensions.
As independent operator we guarantee to provide neutral technical advice and always in the interest of our customers. Confidentiality is guaranteed in all of our activities!
Column Supply
Through our network we supplies >95% of the world’s leading brands. If we cannot supply your specific HPLC column requirement we will be very pleased to recommend an alternative.
Column Lifetime and Stability
The quality and aqueous stability of HPLC silica continues to improve with time. However, the inherent chemical instability of bonded phases at low pH and the dissolution of silicas at high pH remains an underlying problem. Hichrom is able to advise on recommended column usage conditions, column protection and storage.
Troubleshooting Advice
Advice on impurity peaks, sample cleanliness, scale-up and many other HPLC column issues is readily available.
Column Selection
The recent development of numerous new ranges of HPLC columns has complicated the chromatographer’s choice. Our scientists will be very happy to discuss individual’s needs and recommend a column. We maintain a wide-ranging library of general and manufacturers’ literature. Our practical experience in manufacturing and evaluating our own columns, together with those of suppliers and competitors, gives us a wide-ranging knowledge of column selectivity. We are similarly able to advise on column reproducibility and validation criteria.
Applications Data Base
We have world’s largest reference data base of HPLC applications and columns. It currently contains applications involving over 40,000 analytes separated on a wide range of column materials. Approximately 2000 of these applications are related to chiral analyses. Applications cover a broad range of compound areas, including:-
a) Biochemical (eg. peptides and proteins) b) Food c) Ion analysis d) Organics e) Pesticides and environmental f) Pharmaceutical g) Polymers h) Vitamins
Searches can be performed for an individual compound, a mixture of components or a specific column. This proves useful in aiding selection of a suitable column for a particular analysis or in finding alternative columns for a given assay.
Method Strategy
Where suitable, our technical staff are able to discuss and recommend method strategies for customers using the application data base. If appropriate, we will practically develop and optimize the most suitable HPLC method.
Column Screening Service
As the availability of HPLC silicas increases, selection of the optimum column for a particular method is becoming an increasingly onerous task. We maintain an extensive HPLC column library and are well placed to evaluate and advise on selection of the optimum phase.
Method Development and Optimisation Service
Once an HPLC phase has been chosen the optimum column configuration and HPLC conditions need to be selected for required efficiency, speed of analysis, relevant eluent pH, temperature and other practical parameters. We offer both advice and practical support in method development and optimisation procedures.
Column Validation Service
An approved method needs to be checked for robustness and reproducibility. We will evaluate the performance of a method over a period of time. We will also validate the performance of columns manufactured from different batches of the same material.
Wide Range of Silica and Column Dimensions
Please contact us if the packing or column dimensions you require are not listed or standard. We are highly experienced in the manufacture of columns of unique dimensions which are required for a particular application. Additional column hardware geometries are also available.
Customer Supplied Packings
In addition to the manufacture of columns containing commercially available HPLC packings, We routinely manufacture columns of any specified dimension from customer supplied materials. We will be pleased to sign a confidentiality agreement if required.
Batch Reservation Service
We recognises that column to column reproducibility is of utmost importance. Column manufacture is always optimised on the largest available batches of silica. However, for particularly searching applications, we also offer a free batch reservation service which completely eliminates batch related reproducibility concerns. Based on your projected column usage (large or small), we will reserve the quantity of silica you require and pack columns as and when they are required.
Customer enabled equipment design
Although our plant and equipment design is extremely sturdy (compare the weight/price of our pumps with the weight/price of competitive pumps) and easy to handle we cant promise that you never will experience any break down. However, when ever possible we design our pumps in such a way that with a possible equipment breakdown you, our clients will be able to quickly and easily find and exchange the faulty components and without use of complex mechanical and electronic tools. This enable us to get you back in operation in the shortest possible time anywhere on this globe.
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