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How are this benefits achieved?
The Kromasil chromatography bead production is an inversion emulsion process resulting particles with a a wide range of diameters but the same porous structure, pore size and surface area. This uniformity guarantees excellent scale up condition from analytical to prep and production scale chromatography
To the raw silica bead beads is a organo-silane surface attached with a proprietary process and
fused with the underlaying inorganic mechanically very stabile silica bead as a gradient leading to the Eternity platform. The beads have a large surface area of 330 sqm/g and a pore size of 100 Angstrom
To the silanol groups a C18 ligand is being attach and a proprietary endcapping applied. The resultant bead have a carbon loading of only 14% and are stable in a pH range varying from 1 to 12
The uniform Eternity beads are than divide into a wide range of diameters. The 2.5 um and 5 um diameter beads are packed at 1000 bars into UHPLC analytical columns respectively into prep columns
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