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LC Pumps

Types Of Pumps Available in Chromatographyshop

  1. .Reciprocal Piston Pumps,
    1. Analytical,
    2. Semi Prep
    3. Prep Pumps
    4. Production Scale Pumps
      1. for use in Isocratic and Gradient mode  Chromatography
        1. Flash and Medium Pressure Liquid Chromatography (MPLC) (3 bar to 50 bar)
        2. High-Pressure Liquid Chromatography (HPLC) up to 400 bar
        3. Ultra High-Pressure Liquid Chromatography (UHPLC or UPLC) up to 1000 bar
  2.  Syringe Pumps, (For precise dosing in automated applications, diagnostics, etc)
  3. Special Pumps. (Parallel LC Pumps, Valveless Metering  Pumps)

Piston Pumps

Piston Pumps are used to create pressure in the eluent.  The eluent is pumped through a packed Column or cartridge. The column is packed with chromatography beads. The smaller the beads the better the separation resolution.

In chromatography, we require laminar flow without any form of pulsation. Pulsation elimination can be achieved by

  • Using reciprocating piston design with two or three pump heads.
  • Designed stroke length
  • By in-line pulsation damper
  • By complex electronic (software) means.

The basic elements of the pump are a cylindrical pump chamber that holds the piston, a motor that operates a driving cam, a pump seal, and a pair of check valves. As the motor rotates, the piston is moved in and out of the pump chamber. In most pump designs, the pistons are made of sapphire, but also stainless steel and graphite are sometimes used. The check valves serve to control the direction of the flow of the mobile phase through the pump (flow is from bottom to top).

The third dimension is the flow rate of the pump.  We differentiate between

  • Analytical pumps (0.1-10 ml/min Flowrate)
  • Semi-prep Pumps, (1-50 ml/min. Flow rate).
  • Prep-Pumps, (1- 2000 ml/ min flowrate). 
  • Production scale Pumps (multi liter flow rates)

Important components e.g. Check Valve: In their simplest form, the valves comprise a ruby ball and a sapphire seat that is slightly ground (“lapped”) to ensure a leak-free seal when the ball rests on the seat. The valves are open and close in response to pressure and gravity. The pump seal keeps the mobile phase from leaking out around the piston when the pump is under pressure and keeps air from leaking in when the pump is filling.

Economic consideration: The higher the pressure the higher the purchasing and maintenance costs. UHPLC pumps are generally used only in Analytical application to safe time and solvent costs. To reduce maintenance cost many Chromatographer prefer to use 60 MPa pumps

Maintenance Consideration: It depends on the user’s perspective. If you maintain the equipment yourself you should go for the high-quality pumps with traditional engineering.  LCC Consensus Pumps are very solidly built (Heavier than other pumps ) and run for 20 and more years maintenance-free.  With other pumps, you need software specialists and maintenance contracts.

Such Pumps are used also in other applications such as SFC, injection, and Geological research.

Syringe Pumps

Syringe Pumps are used for very precise volumes dosing in a wide range of applications such as Diagnostic manufacture or sample injections etc.  Most pumps are custom built to specific applications ranging from nano, micro, and ml dosing.

Consensus Syringe Pumps dose with extremely high accuracy and pulsation-free from ml, ul down to nl range. 

A syringe pump may have one or many syringes. The piston is connected with a stepper motor that moves the plunger without vibration to deliver exudes extremely smoothly.

Syringes can also be exchanged with sterilizable and chemically inert  glass syringes or Polymer-based syringes

Consensus Syringe Pumps are for a wide range of challenging applications in research, industry, and development, There are applications in the field of flow chemistry, in-vitro diagnostics, micro-reactions equipment, and microfluidics. They all depend on pulsation-free performance in the creation of fluid streams. This is because small flow rates in the nanoliter range require utmost precision and incredibly smooth operation. When using our syringe pumps, you can rely on highly accurate mechanical components, enabling continuous processes, improved product quality, production flexibility, and cost-effectiveness.

 Consensus syringe pumps are used with the following application:

  1. Dosing of reaction solutions for screening applications and miniaturized syntheses in microfluidics
  2. Highly accurate fluid dosing and creation of minimal, precisely defined fluid streams
  3. Various lab-on-chip applications, such as DNA amplification (PCR chip)
  4. Creation of micro-serial sample flows in high-throughput applications
  5. Dosing of reagents with periodical gradients for the creation of compartment sequences with variable concentration of ingredients (creation of parameter spaces, e.g. inactive agent researchInfusing calibrant into a mass spectrometer or reaction chamber.
  6. Long term drug infusions to animals and general infusion applications.

Specials Pumps

Parallel LC Pumps P10 with  Ten Heads

This pump contains ten pump heads and pistons that are consolidated in two blocks of five heads. The pump is designed for parallel Flash and MPLC operations. The Pump heads are made from high-quality SS 1.4571. 

Our Parallel  LC Pump is used in a number of custom manufactured High Through Put system!

High Through Put System must be engineered to customer requirements.  Every client has a different set of circumstances and needs.   It is important that all variables are taken into consideration (Operators, Skill level, output, chemical engineering, costs, etc)

Please contact us for preliminary discussions. We have more than 20 years of experience in developing many different parallel technologies. We can satisfy any customer’s requirements and budget.

Gradient Flash & Fraction Collector
Parallel Flash System with 5 disposable Cartridges, Gradient Former and Fraction Collector
Parallel Flash 5
Gradient parallel Flash with 5 disposable flash cartridges, UV detector, and fraction collector
10 parallel Flash in Diagnostics plant
Diagnostic manufacturing plant using isocratic 10 parallel Flash cartridges


Consensus Valveless Metering  Pump E 200

For dosing liquid chemicals, solvents, suspensions, etheric oils, and oils in food applications

Functional principle

The piston is flattened at the front to about 65% of the diameter. Dosing is accomplished by the synchronous rotation and reciprocation of the ceramic piston in the precisely mated ceramic cylinder liner. One complete piston revolution is required for each suction/discharge cycle. In the suction phase [1], the pressure side is blocked, the axial movement is sucked in since the piston performs a rotating and axial rotation at the same time. The piston reaches a so-called 0 position in the rear position [2], that is, the input and output sides are blocked. In the forward movement [3], the pressure side is released and the suction side is blocked. After this, the piston is in the forward position [4]. The process is then repeated.

Valvless Pump Mechanism
Metering Pump for Medical, Laboratory, and Industrial Application