Description
PIC-Lab Hybrid SFC means: “A single device/instrument for performing multiple processes such as method development, semi-preparative separations and fraction analyses.
Applications in the chiral and achiral separation of small molecules, peptides and natural products.
This versatility saves money and time
Key features
- Individual channels for each analytical and preparative SFC ensure reproducibility and robustness
- Automatic change of columns (9 analytical columns, 6 preparative columns) and up to 6 solvents
- Instrument operation is controlled by a Program Logic Controller (PLC) providing high reliability and reproducibility.
- Proprietary software on a desktop station allows the user to program sequences, visualize data and process it.
- Intelligent software facilitates sorting of methods for rapid screening and ranking of results to assist the user in rapid method selection.
- Stacked and non-stacked injections are possible in manual, automatic and extraction modes
- CO2 recycling reaches 90-95% efficiency
- Wide choice of detectors: UV, ELSD and single-quad mass spectrometer
- Fully automatic collection by time or detector-specific threshold
- PIC-Lab Hybrid SFC 20, 10-100 and 10-150 are designed for micro-scale separations, milligram to gram scale, with flow rates from 20 to 150 mL/min and are ideal for columns with an inner diameter of 10 mm, 20 mm and 30 mm.
- The PIC-Lab Hybrid SFC series is also available as an open-bed system.
PIC-Lab Hybrid range
- PIC-Lab Hybrid 20 SFC
- PIC-Lab Hybrid 10-10 SFC
- PIC-Lab Hybrid 10-150 SFC
The PIC-Lab Hybrid range is designed for separations on a micro scale, milligram to gram scale, with flow rates from 20 to 150 mL/min and is ideal for columns with an internal diameter of 10 mm, 20 mm and 30 mm. The PIC-Lab Hybrid SFC series is also available as an open-bed system.
PIC-Lab Hybrid 20 SFC
A single system for performing method development, preparative separations and fraction analyses.
Applications in the chiral and achiral separation of small molecules, peptides and natural products.
Features
- – Parallel analytical and preparative pathways for maximum performance
- – UV, ELSD, MS and time collection
- – Highly efficient GLS for maximum recovery
- – “One machine – multiple uses” to minimise lab space and costs
- – Efficient CO2 recovery
- – SFE-SFC (X-injection) possible
- – Automated switching between analytical and preparative channels
- – Automated switching valves for analytical and preparative columns and for selection of up to 6 co-solvents.
- – Precise composition of the mobile phase by injecting the co-solvent at constant pressure
Specifications
- PIC-Lab Hybrid 20 SFC Analytical mode
- Production capacity 0.2-5g/day
- Maximum flow rate 20 ml/min 10 ml/min
- Column size 10, 20 mm id 4.6 mm id
- Column change 1-4 preparation columns Up to 10 analytical columns
- Co-solvent Flow rate max. 10 ml/min max. 10 ml/min
- CO2 supply Gaseous or liquid CO2 at 50 bar
- Co-solvent change Up to 6 solvents Maximum pressure 300 bar
- Temperature 15 to 60°C
- Collection 4-5 fractions plus waste
- CO2 recycling Yes No
- Reliable stacked injection with a syringe pump through a valve system separate from the analysis channel.
- Easy-to-use software to develop methods, process and visualise data.
- One-click conversion of a single injection table into a stacked injection.
- High robustness, repeatability and reliability with Process Logic Controller (PLC) for unit operational control.
- Benchtop format (140 x 75 x 120 mm)
- Current requirement 250 / 20 A
PIC-Lab Hybrid 10-100 SFC
A single system for performing method development, preparative separations and fraction analyses.
Applications in chiral and achiral separation of small molecules, peptides and natural products.
Features
- – Parallel analytical and preparative pathways for maximum performance
- – UV, ELSD, MS and time collection
- – – Highly efficient GLS for maximum recovery
- – “One machine – multiple use” to minimise lab space and costs
- – Efficient CO2 recovery
- – SFE-SFC (X-injection) possible
- – Automated switching between analytical and preparative channels
- – – Automated switching valves for analytical and preparative columns and for up to 6 co-solvents to choose from.
- – Precise composition of the mobile phase by
- – introduction of co-solvent at constant pressure
Specifications
- PIC-Lab Hybrid 10-100 SFC Analytical Mode
- production capacity 3-25g/day
- maximum flow rate 100 ml/min 10 ml/min
- column size 10, 20 & 30 mm id 4.6 mm id
- column change 1-4 preparation columns Up to 9 analytical columns
- co-solvent flow rate max 50 ml/min max 10 ml/min
- CO2 supply Gaseous or liquid CO2 at 50 bar
- co-solvent switching Up to 6 solvents
- maximum pressure 300 bar
- temperature 15 to 60°C
- collection 4-5 fractions plus waste –
- reliable stacked injection with a syringe pump through a valve system separate from the analysis channel.
- easy-to-use software for developing methods, processing and visualising data.
- one-click conversion of a single injection table into a stacked injection.
- high robustness, reproducibility and
- reliability with Process Logic Controller (PLC) for unit operation control.
- CO2 recycling Yes No
- tabletop unit format (140 x 75 x 120 mm)
- power consumption 250 V / 20 A
PIC-Lab Hybrid 10-150 SFC
A single system for performing method development, preparative separations and fraction analyses.
Applications in chiral and achiral separation of small molecules, peptides and natural products.
Features
- – Parallel analytical and preparative pathways for maximum performance
- – UV, ELSD, MS and time collection
- – – Highly efficient GLS for maximum recovery
- – “One machine – multiple use” to minimise lab space and costs
- – Efficient CO2 recovery
- – SFE-SFC (X-injection) possible
- – Automated switching between analytical
- – and preparative channels
- – – Automated switching valves for analytical and preparative columns and for the selection of up to 6 co-solvents.
- – Precise composition of the mobile phase by injecting the co-solvent at constant pressure.
Specifications
- PIC-Lab Hybrid 10-150 analytical mode
- production capacity 3-25g/day
- maximum flow rate 150 ml/min 10 ml/min
- column size 10, 20 & 30 mm id 4.6 mm id
- column change 1-4 preparation columns Up to 9 analytical columns
- co-solvent flow rate max 50 ml/min max 10 ml/min
- CO2 supply Gaseous or liquid CO2 at 50 bar
- co-solvent switching Up to 6 solvents
- maximum pressure 300 bar
- temperature 15 to 60°C
- collection 4-5 fractions plus waste –
- reliable stacked injection with a syringe pump through a valve system separate from the analysis channel.
- easy-to-use software for developing methods, processing and visualising data.
- conversion of a single injection table with one click into
- stacked injection.
- high robustness, reproducibility and reliability with Process Logic Controller (PLC) for unit operation control.
- CO2 recycling Yes No
- tabletop unit format (140 x 75 x 120 mm)
- power consumption 110 / 20 A