Description

The PIC-Lab SUPER SFC series is designed for large scale purification of enantiomers and complex mixtures of small molecules, peptides, hemp extracts and natural products.

For larger scale purification, the efficient and sustainable CO2 separation technology (SFC) drastically reduces operating costs as it is faster, recycles CO2, uses less energy and has much less solvent compared to HPLC.

This fully automated system is equipped with a UV-Vis as a standard detector and a co-solvent pump to allow isocratic or gradient procedures.

Configurations with other detectors such as ELSD, CAD and single quad mass spectrometers are also available on request.

General essential features

1. the CO2 diaphragm pump is highly accurate, durable, reliable and highly efficient
2. stacked injection with seamless injection module for fast and reliable cycles
3. back-pressure regulator based on a robust and intelligent PIC solution
4. detection with UV, ELSD detectors or single quad mass spectrometer on request
5. instrument operation is controlled by a Programmable Logic Controller (PLC) for continuous, reliable, robust and unattended operation.
6. PIC-Lab’s own user-friendly software is used for method programming and data visualisation.

 

PIC-Lab SUPER SFC product range

1. PIC-Lab SUPER SFC 200
2. PIC-Lab SUPER SFC 400
3. PIC-Lab SUPER SFC 600
4. PIC-Lab SUPER SFC 800

 

1. PIC-Lab SUPER SFC 200

Features:

• Maximum flow rate (mL/min) 200
• Column i.d. 30 mm, 50 mm
• Estimated throughput/day 15-500g
• Number of columns: Up to 4 preparative columns
• Detectors; standard UV-VIS ELSD, CAD, MS and time registration
• Fully automated systems for purification of enantiomers and complex mixtures of small molecules, peptides and natural products, including cannabis/hemp extracts.

Specifications

1. PIC-Lab SUPER SFC 200
2. Maximum flow rate 200 ml/min (LEWA membrane pump)
3. Production capacity 5-40g/day
4. Column size 30 & 50 mm i.d.
5. High-efficiency GLS for maximum recovery
6. UEFE-SFC (X-injection) and extraction mode enabled
7. Efficient CO2 recovery
8. Process logic control (PLC) ensures high robustness, reproducibility and reliability
9. Accurate mobile phase composition by adding co-solvent at constant pressure
10. Easy-to-use software with one-click conversion to stacked injection sequence
11. Column/co-solvent changeover 1-4 prep columns; up to 4 solvents
12. Co-solvent Flow rate max. 100 ml/min
13. CO2 supply Gaseous or liquid CO2 at 50 bar
14. Temperature, maximum pressure 15 to 60°C, 350 bar
15. Collection 4 (5 as an option) fractions plus waste
16. CO2 recycling Yes
17. Format Free-standing frame (140 x 75 x 180 cm, 55x29x71 in)
18. Power requirements 208 V 3-phase / 30 A

 

2. PIC-Lab SUPER SFC 400

Main features

• Up to 4 preparative columns
• UV, ELSD, CAD, MS and time recording
• Highly efficient GLS for maximum recovery
• SFE-SFC (X-injection) and extraction mode enabled
• Efficient CO2 recovery
• Process logic control (PLC) ensures high robustness, reproducibility and reliability
• Accurate mobile phase composition by adding co-solvent at constant pressure
• Easy-to-use software with one-click conversion to stacked injection sequence
• Fully automated systems for purification of enantiomers and complex mixtures of small molecules, peptides and natural products, including cannabis/hemp extracts.

Specifications

1. PIC-Lab SUPER SFC 400
2. Production capacity 15-600g (1000) /day
3. Maximum flow rate 400 ml/min (LEWA membrane pump)
4. Column size 30, 50, 76 mm i.d.
5. Column/cosolvent exchange 1-4 prep columns; up to 4 solvents
6. Co-solvent Flow rate max. 100 ml/min
7. CO2 supply Gaseous or liquid CO2 at 50 bar
8. Temperature, maximum pressure 15 to 60°C, 350 bar
9. Collection 4 (5 as an option) fractions plus waste
10. CO2 recycling Yes
11. Format Free-standing frame (170 x 80 x 180 cm, 67x31x71 in)
12. Power requirements 208 V 3-phase / 30 A

 

3. PIC-Lab SUPER SFC 600

Main features

• Up to 4 preparative columns
• UV, ELSD, CAD, MS and time recording
• Highly efficient GLS for maximum recovery
• SFE-SFC (X-injection) and extraction mode enabled
• Efficient CO2 recovery
• Process logic control (PLC) ensures high robustness, reproducibility and reliability
• Accurate mobile phase composition by adding co-solvent at constant pressure
• Easy-to-use software with one-click conversion to stacked injection sequence
• Fully automated systems for near-process purification of enantiomers and complex mixtures of small molecules, peptides and natural products, including cannabis/hemp extracts.

Specifications

1. PIC-Lab SUPER SFC 600
2. Production capacity 30-1200g (1500) /day
3. Maximum flow rate 600 ml/min (LEWA diaphragm pump)
4. Column size 30, 50, 76 mm i.d.
5. Column/cosolvent exchange 1-4 prep columns; up to 4 solvents
6. Co-solvent Flow rate max. 100 ml/min
7. CO2 supply Gaseous or liquid CO2 at 50 bar
8. Temperature, maximum pressure 15 to 60°C, 350 bar
9. Collection 4 (5 as option) fractions plus waste
10. CO2 recycling Yes
11. Freestanding rack (170 x 80 x 180 cm, 67x31x71 in)
12. Format Power requirement 208 V 3-phase / 30 A

 

4 PIC-Lab SUPER SFC 800

Main features

• Up to 4 preparative columns
• UV, ELSD, CAD, MS and time recording
• Highly efficient GLS for maximum recovery
• SFE-SFC (X-injection) and extraction mode enabled
• Efficient CO2 recovery
• Process logic control (PLC) ensures high robustness, reproducibility and reliability
• Accurate mobile phase composition by adding co-solvent at constant pressure
• Easy-to-use software with one-click conversion to stacked injection sequence
• Fully automated system for near-process purification of enantiomers and complex mixtures of small molecules, peptides and natural products, including cannabis/hemp extracts

Specifications

1. PIC-Lab SUPER SFC 800
2. Production capacity 40-1350g (2000) /day
3. Maximum flow rate 800 ml/min (LEWA membrane pump)
4. Column size 30, 50, 76 mm i.d
5. Column/cosolvent exchange 1-4 prep columns; up to 4 solvents
6. Co-solvent Flow rate max. 100 ml/min
7. CO2 supplies gaseous or liquid CO2
8. Temperature, maximum pressure 15 to 60°C, 350 bar
9. Collection 4 (5 as an option) fractions plus waste
10. CO2 recycling Yes
11. Format Free-standing frame (190 x 80 x 200 cm, 74x31x79 in)
12. Power requirements 208 V 3-phase / 30 A.

Check similar products below