Description

Newcrom B HPLC Column is packed with multimode 100A hydrophobic ligand and with a positve charged terminal functional group

Structure of Product Description: Column

Description-Column ID x Column lengt(mm)-Particle Diameter um – Pore Diameter (A)/Article No.

Newcrom BH HPLC Column is an interesting novel multimode column

This was achieved by attaching a long alkyl chain to the silica gel surface and placing an ion-exchange group at the terminal end of this chain.  As a result, the ion-exchange functional groups have high mobility inside the pores of the solid particles. This eliminates the chelating (trapping) effect observed with multi-charged analytes on a surface of traditional ion-exchangers. The embedded ion-exchange groups in Newcrom behave as ions in a solution not as ions on a surface. While highly mobile, they can not go beyond the length of the ligand chain.

Chromatography related to ion-exchange process thus still takes place. Ions of opposite charge can be retained and separated based on their charge, ion size, and polarization ability.  Also, reverse-phase nature of the stationary phase allows ion separation based on their hydrophobic properties, charge position in the molecular skeleton and isomeric structure of none-charged part of the molecule.

Newcrom B  HPLC Columns are available in all standard dimensions

Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm
Column Lengths: 250, 150, 100, 50, 25, 10 mm
Particles: 5 µm and 3 µm
Pores: 100 A

Newcrom B Application Examples

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